The Berkeley Open Infrastructure for Network Computing, (BOINC), is an open-source middleware system that supports volunteer and grid computing. Originally developed to support the SETI@home project, it became generalized as a platform for other distributed applications in areas as diverse as mathematics, linguistics, medicine, molecular biology, climatology, environmental science, and astrophysics, among others. BOINC aims to enable researchers to tap into the enormous processing resources of multiple personal computers around the world.
BOINC - https://boinc.berkeley.edu

Folding@home (FAH) is a distributed computing project for disease research that simulates protein folding, computational drug design, and other types of molecular dynamics. Its main purpose is to determine the mechanisms of protein folding, which is the process by which proteins reach their final three-dimensional structure, and to examine the causes of protein misfolding.
FAH - https://foldingathome.org